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. 2020 Jul 22;9(8):650. doi: 10.3390/antiox9080650

Figure 4.

Figure 4

Compound 4g protects against acute toxicity induced by OA in hippocampal slices: (A) Representative H2DCFDA fluorescence images of hippocampal slices treated with OA in presence or absence of 4g (10 μM) or melatonin (10 μM) during 6 h. (B) Cell viability of hippocampal slices treated with saline (Basal), OA (1 μM), OA (1 μM) + 4g (10 μM) or OA (1 μM) + melatonin (Mel, 10 μM) during 6 h. Cell viability was then evaluated by MTT reduction assay and normalized to basal conditions (100%). (C) Quantitation of H2DCFDA fluorescence intensity as free radical production measurement after the experimental conditions described in (B). Data are expressed as mean ± S.E.M of four different experiments. ## p < 0.01, ### p < 0.001 compared to basal condition; ** p < 0.01, *** p < 0.001, compared to OA treated hippocampal slices.