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. 2020 Jul 31;12(8):2128. doi: 10.3390/cancers12082128

Table 1.

Summary of the clinicopathological features of hepatocellular carcinomas (n = 285).

Parameters Frequency (%) or Median (Range)
Sex, n (%)
Male 216 (75.8)
Female 69 (24.2)
Age at operation, median (range, years) 63 (29–87)
Etiology, n (%)
Hepatitis B virus (HBV) 202 (70.9)
Hepatitis C virus (HCV) 25 (8.8)
HBV + HCV 1 (0.3)
Alcohol 14 (4.9)
Non-alcoholic fatty liver disease 12 (4.2)
Uncertain etiology 31 (10.9)
Tumor size, median (range, cm) 3.2 (0.9–17)
Multiplicity present, n (%) 49 (17.2)
Edmondson–Steiner grade, n (%)
Grade I 3 (1.0)
Grade II 77 (27.0)
Grade III 171 (60.0)
Grade IV 34 (12.0)
Microvascular invasion present, n (%) 113 (39.6)
Portal vein invasion present, n (%) 19 (6.7)
Pathologic T category (AJCC 8th edition), n (%)
pT1a 37 (13.0)
pT1b 101 (35.4)
pT2 112 (39.3)
pT3 11 (3.9)
pT4 24 (8.4)
Extrahepatic metastasis present, n (%) 55 (19.3)
Cirrhosis in background liver present, n (%) 152 (533.3)
Recurrence on follow-up present, n (%) 161 (56.5)
Status at last follow-up, n (%)
Alive 128 (44.9)
Deceased of disease 44 (15.4)
Deceased of other cause 10 (3.5)
Follow up loss 103 (36.2)
Overall survival, median (range, months) 66.5 (0–163)
Disease-free survival, median (range, months) 32.5 (0–163)

AJCC, American Joint Committee on Cancer.