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Flow chart representing the study design. The mice were divided into 4 groups after the acclimatization period. The normal diet (ND) mice received a standard chow diet during the complete 8-week study period. Similarly, the HFD group received a high-fat diet during the complete 8-week study period. However, the HFDO (HFD + Orlistat) and HFDM (HFD + Mangifera indica seed kernel (MESK)) groups were given respective treatments from the third week onwards until the end of the study.
