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Effect of high-fat diet on fat deposition in the HFD-fed obese mice at 10× and 40× magnifications. Treatment with MESK completely prevented hepatic lipid deposition and hepatic ballooning. (A: ND: normal diet, B: HFD: high-fat diet, C: HFDO: HFD + Orlistat, D: HFDM: HFD + MESK). HPV: Hepatic portal vein, Lipid accumulation: fat droplets. Scale bar indicates 2000 µm.
