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Results of in vitro permeability study. Flux (J); permeability coefficient (Kp) and relative permeability at 15 min (RP15 min) values of MEL-loaded polymeric micelles compared to crystalline MEL.
| Samples | J (µg/cm2/h) | Kp (cm/h) | RP15 min |
|---|---|---|---|
| Crystalline MEL | 7.67 | 0.005752 | 1.00 |
| Pol_mic1 | 127.33 | 0.095550 | 5.35 |
| Pol_mic2 | 110.32 | 0.082746 | 4.56 |
| Pol_mic3 | 127.02 | 0.095277 | 5.80 |
| Average (formulations) | 121.56 | 0.091191 | 5.24 |
| SD (formulations) | 9.73 | 0.007315 | 0.63 |
