Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2020 Jul 27;8(8):1125. doi: 10.3390/microorganisms8081125

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2020 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

PMC Copyright notice

Detection of HPyV6, HPyV7, and MCPyV on the translational level in FFPE of CCA and non-neoplastic hepatocytes. (a) Representative examples of IHC using 2t10 antibodies showed the specific nuclear expression in the nucleus (brown) of both CCA and liver parenchyma. CCA2 tissue is an example of negative HPyV7. (b) In a representative IHC for CCA15 tissue, 1t1 antibodies show positivity in both CCA and hepatocytes, while no protein expression was seen in CCA3. (c) Example of results of IHC for MCPyV, specific nuclear expression (brown) of MCPyV (CM2B4 antibody) in the nuclei of CCA epithelial, and the non-neoplastic hepatocytes. MKL1 cell line served as a positive for MCPyV antibodies. The images were taken at 200x magnification, a black square area was magnified 6x in the top right corner of each figure.