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. 2020 Aug 11;12(8):1800. doi: 10.3390/polym12081800

Table 5.

Summary of structural, physical, and physico-chemical properties of hyaluronic acid with various molecular weights.

Property HA MW, kDa Authors Reference
Hydrodynamic size 100, 500, 1000, 3000, 6000 Cowman et al. [40]
Rheology 350, 680, 1800 Falcone et al. [49]
1000, 2000, 3000, 4000 Bothner et al. [50]
125, 241, 390, 598, 800, 961, 1270, 1430, 1620, 1770, 2040, 2150 Yanaki and Yamaguchi [54]
Surface tension 100, 500, 4000 Knepper et al. [59]
1630 Ribeiro et al. [60]
1500 Krause et al. [61]
807, 4280, 5560 Silver et al. [62,64]
1000, 5000 Nepp et al. [66]
Cohesion/adhesion 350, 680, 1800 Falcone et al. [49]
132, 1500, 2000 Vorvolakos et al. [69]
Density 1500 Gómez-Alejandre et al. [75]
1430 García-Abuín et al. [76]
10–30, 110–130, 300–500, 1500–1750 Kargerová and Pekař [80]
Ultrasound velocity 1430 García-Abuín et al. [76]
10–30, 110–130, 300–500, 1500–1750 Kargerová and Pekař [80]
Osmolality and colloid osmotic pressure 1000, 2000, 3000, 4000 Bothner et al. [50]
From 500 to 7900 (eye drops) Dick et al. [93]
Dick [94]
Hydraulic conductivity and fluid absorption rate 85, 280, 500, 4000 Wang et al. [102]
45.4, 81.9, 165, 196, 699, 844, 1110 Lam [104]
Lam and Bert [105]