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. 2020 Aug 5;12(8):2182. doi: 10.3390/cancers12082182
MCL1 Myeloid cell leukemia sequence 1
BCL2 B-cell CLL/lymphoma 2
BIM BCL2-like 11 (apoptosis facilitator)
PARP Poly ADP-ribose polymerase 1
NOXA Phorbol-12-myristate-13-acetate-induced protein 1
BID BH3 Interacting Domain Death Agonist
CASP8 Caspase 8
PDCD4 Programmed cell death protein 4
CRISPR Clustered regularly interspaced short palindromic repeats
BRAF B-Raf proto-oncogene
BH3 Bcl-2 Homology 3
ABT-199 Abbott Laboratories, a Bcl-2 selective BH3 mimetic
FDA U.S. Food and Drug Administration
RAS Rat sarcoma family of oncogenes
NF1 Neurofibromin 1
NRAS Neuroblastoma RAS Proto Oncogene
SEM Standard error of the mean
MEK Mitogen-activated protein kinase family