MCL1 |
Myeloid cell leukemia sequence 1 |
BCL2 |
B-cell CLL/lymphoma 2 |
BIM |
BCL2-like 11 (apoptosis facilitator) |
PARP |
Poly ADP-ribose polymerase 1 |
NOXA |
Phorbol-12-myristate-13-acetate-induced protein 1 |
BID |
BH3 Interacting Domain Death Agonist |
CASP8 |
Caspase 8 |
PDCD4 |
Programmed cell death protein 4 |
CRISPR |
Clustered regularly interspaced short palindromic repeats |
BRAF |
B-Raf proto-oncogene |
BH3 |
Bcl-2 Homology 3 |
ABT-199 |
Abbott Laboratories, a Bcl-2 selective BH3 mimetic |
FDA |
U.S. Food and Drug Administration |
RAS |
Rat sarcoma family of oncogenes |
NF1 |
Neurofibromin 1 |
NRAS |
Neuroblastoma RAS Proto Oncogene |
SEM |
Standard error of the mean |
MEK |
Mitogen-activated protein kinase family |