Table 2.

Test metrics, patient group epilepsy vs. control comparison.

Panel I	% LOOCV Mean (SD) Group 1	% LOOCV Mean (SD) Group 2		True Positive Group 1		False Positive Group 2	True Negative Group 2	False Negative Group 1	N		Figure #
Group 1 vs. Group 2
Ion-Trap MS LOOCV Data Sets:
Epilepsy vs. Control	55.09%	31.81%		29/29		0/17	17/17	0/29	Epilepsy = 29; Control = 17		Figure 1C
	(4.84%)	(3.58%)		(100%)		(0%)	(100%)	(0%)
Training: Epilepsy vs. Control	56.98%	28.60%		23/23		0/13	23/23	0/23	Epilepsy = 6; Control = 4		Figure 2B
	(4.28%)	(−4.42%)		(−100%)		(0%)	(100%)	(0%)
Blind: Epilepsy vs. Control	47.58%	29.69%		13/13		0/16	16/16	0/13	Epilepsy = 23; Control = 13		Figure 2A
	(3.6%)	(1.18%)		(100%)		(0%)	(100%)	(0%)
TBI vs. Epilepsy	69.73%	29.69%		13/13		0/16	16/16	0/13	TBI = 13; Epilepsy = 16		Figure 3B
	(4.48%)	(5.87%)		(100%)		(0%)	(100%)	(0%)
Single Quadrupole MS LOOCV Set:
Epilepsy vs. Control	47.98% (10.48%)	24.10% (9.05%)		27/29 (93.1%)		2/17 (12%)	15/17 (88.2%)	2/29 (6.9%)	Epilepsy, N = 29; Control, N = 17		Figure 2C
Panel II	Sens-itivity	Efficiency/ [accuracy]	True Positive Rate		False Positive Rate	Spec-ificity	P- value	Random Database P-value	Coh-en’sd	ROC AUC	Figure#
group 1 vs. group 2
Ion-Trap MS LOOCV Data Sets
Epilepsy, N = 29 vs. Control, N = 17	1	1	1		0	0.97	4.56 × 10−22	0.108	5.46	1	Figure 1C,D
Training: Epilepsy, N = 23 vs. Control, N = 13	1	1	1		0	1	3.02 × 10−16	0.054	6.52	1	Figure 2A
Blind: Epilepsy, N = 6 vs. Control N = 4	1	0.9	1		0.25	0.75	5.62 × 10−3	na	2.07	1	Figure 2B
TBI, N = 13 vs. Epilepsy, N = 16	1	1	1		0	1	2.00 × 10−15	0.0012	7.66	1	Figure 3B,
Single Quadrupole MS LOOCV Set:
Epilepsy, N = 29 vs. Control, N = 17	0.9	0.87	0.9		0.018	0.82	3.95 × 10−10	0.37	2.43	0.953	Figure 2C,D