Strengths:

Simple, cheap, and accurate results in most cases [42]

Limitations:

Lack of sensitivity and specificity, because TBA reacts with different compounds, namely sugars, amino acids, bilirubin, and albumin [42] MDA is unstable for a long period of time, since it oxidizes into alcohols and acids [42] Aldehydes may also react with TBA, leading to an overestimation of MDA [45]