Table 4.
Associations of age and magnitude of BMI at peak (per 1 SD increment in each metric) with metabolite network scores derived from untargeted metabolomics data at the early teen visit (median age 12.8 years) for boys and girls in Project Viva a.
| Boys | Girls | |||
|---|---|---|---|---|
| Y-Variable: Age at Peak | Y-Variable: Magnitude of BMI at Peak | |||
| X-variable | β (95% CI) per 1.85 mo | P | β (95% CI) per 1.32 kg/m2 | P |
| ME1 | −0.001 (−0.005, 0.003) | 0.51 | 0.000 (−0.008, 0.008) | 0.99 |
| ME2 | −0.0057 (−0.013, 0.002) | 0.12 | 0.004 (−0.004, 0.012) | 0.37 |
| ME3 | −0.006 (−0.013, 0.001) | 0.11 | −0.003 (−0.010, 0.005) | 0.54 |
| ME4 | −0.002 (−0.009, 0.005) | 0.57 | 0.009 (0.001, 0.017) | 0.03 |
| ME5 | 0.001 (−0.007, 0.008) | 0.84 | 0.004 (−0.004, 0.012) | 0.34 |
| ME6 | −0.004 (−0.011, 0.004) | 0.23 | 0.003 (−0.005, 0.010) | 0.52 |
| ME7 | 0.003 (−0.004, 0.011) | 0.36 | 0.003 (−0.005, 0.011) | 0.52 |
| ME8 | −0.004 (−0.011, 0.004) | 0.33 | 0.001 (−0.007, 0.009) | 0.77 |
| ME9 | −0.002 (−0.009, 0.006) | 0.67 | −0.002 (−0.010, 0.006) | 0.67 |
| ME10 | −0.003 (−0.010, 0.004) | 0.43 | 0.003 (−0.005, 0.011) | 0.49 |
| ME11 | 0.005 (−0.002, 0.013) | 0.17 | 0.001 (−0.007, 0.009) | 0.88 |
| ME12 | −0.006 (−0.013, 0.001) | 0.09 | −0.003 (−0.011, 0.005) | 0.43 |
| ME13 | 0.003 (−0.004, 0.010) | 0.44 | 0.003 (−0.006, 0.011) | 0.52 |
a—Estimates are adjusted for race/ethnicity and age at the early teen visit. Bolded values indicate statistical significance at alpha = 0.05.