Skip to main content
. 2020 Jul 26;9(8):666. doi: 10.3390/antiox9080666
8-OHdG 8-hydroxydeoxyguanosine
AGE advanced glycation end-products
ARPE-19 adult retinal pigment epithelial cell line-19
BDNF brain-derived neurotrophic factor
BK bradykinin
BRB blood–retinal barrier
COX-2 cyclooxygenase
CTGF connective tissue growth factor
CyA cyclosporine A
DM diabetes mellitus
DR diabetic retinopathy
EC endothelial cells
Egr-1 early growth response protein 1
eNOS endothelial nitric oxide synthase
EP ethyl pyruvate
ERK extracellular signal-regulated kinase
GA glycyrrhizin
GSH reduced glutathione
HIF-1α hypoxia induced factor-1α
HMGB high-mobility group box
HO-1 heme oxygenase-1
HRECs human retinal endothelial cells
HRMEC human retinal microvascular endothelial cells
ICAM-1 intercellular adhesion molecule-1
IFN interferon
IGFBP-3 insulin-like growth factor-binding protein-3
IL interleukin
iNOS inducible nitric oxide synthase
MAPK mitogen-activated protein kinase
MMP-9 metalloproteinases-9
NF-κB nuclear factor-κB
NOX nicotinamide adenine dinucleotide phosphate oxidase
NPDR non proliferative diabetic retinopathy
OPN osteopontin
PAI-1 plasminogen activator inhibitor-1
PARP poly ADP-ribose polymerase
PCE polygonum cuspidatum
PDR proliferative diabetic retinopathy
PEDF pigment epithelium-derived factor
PI3K phosphatidylinositol 3-kinase
PK protein kinase
PLA-2 phospholipases A2
PVR proliferative vitreoretinopathy
RAGE receptors for AGEs
RGC retinal ganglion cells
ROP retinopathy of prematurity
ROS reactive oxygen species
RPE retinal pigmented epithelium
shRNA short hairpin RNA
siRNA small interfering RNAs
SIRT sirtuin
SOCS3 suppressor of cytokine signaling 3
SOD superoxide dismutase
STAT-3 signal transducer and activator of transcription-3
pSTAT-3 phosphorylated STAT-3
STZ streptozotocin
TGF-β1 transforming growth factor-β1
TLR toll like receptor
TNF-α tumor necrosis factor-α
TYK2 tyrosine kinase 2
VAP-1 vascular adhesion protein-1
VCAM-1 vascular cell adhesion molecule-1
VEGF vascular endothelial growth factor