Table 1.
Main clinical and biological features of a multicenter sample of 444 polypathological patients recruited for sarcopenia and frailty assessment.
| Clinical Features | Mean (SD)/Median -IQR-/N (%) |
|---|---|
| Number of defining categories (major diseases) per patient | 2.5 (0.5) |
| Prevalence of defining categories (major diseases) | |
| Heart diseases | 374 (84.6%) |
| Kidney/autoimmune diseases | 202 (45.7%) |
| Lung diseases | 183 (41.4%) |
| Neurological diseases | 133 (30.1%) |
| Peripheral arterial disease/diabetes with neuropathy | 80 (18.1%) |
| Neoplasia/chronic anemia | 70 (15.8%) |
| Degenerative osteoarticular disease | 43 (9.7%) |
| Liver disease | 28 (6.3%) |
| Number of other comorbidities per patient | 5.9 (2.3) |
| Most frequent comorbidities | |
| Hypertension | 380 (86%) |
| Dyslipemia | 232 (52.5%) |
| Diabetes with no visceral involvement | 216 (49%) |
| Atrial fibrillation | 178 (40%) |
| Obesity | 159 (36%) |
| Anxiety and depressive disorders | 74 (17%) |
| Benign prostate hyperplasia | 64 (14.5%) |
| Frequent symptoms | |
| Fatigue | 304 (70%) |
| Anorexia | 212 (48%) |
| Insomnia | 194 (44%) |
| Chronic pain | 178 (40%) |
| Cough | 158 (36%) |
| Patients with basal III-IV class of NYHA//III–IV class of mMRC | 128 (29%) |
| PROFUND index | 6 -6- |
| Basal Barthel’s Index | 66 (30) |
| BMI (Kg/m2) | 30 (6.6%) |
| Main biological parameters | |
| Hemoglobin (d/dL) | 11.3 (2) |
| Creatinin (mg/dL) | 1.26 (1) |
| Albumin (g/dL) | 3.2 (0.9) |
| Cholesterol (mg/dL) | 151 (42) |
| Triglicerydes (mg/dL) | 116 -80- |
| Vitamin D (ng/mL) | 11 -17- |
| Leucocytes (n°/µL) | 8000 -4000- |
| Lymphocytes (n°/µL) | 1200 -400- |
SD: standard deviation; IQR: interquartile range; NYHA: New York Heart Association; mMRC: Medical Research Council. BMI: body mass index.