Table 3.
Results of the validation of miRNA candidates by qPCR in the independent cohort of PDAC patients.
| microRNA | NGS Discovery Cohort | qPCR Group Comparison Validation Cohort | qPCR Survival Analysis Validation Cohort | ||
|---|---|---|---|---|---|
| Log2FC | p-Value | Log2FC | p-Value | p-Value | |
| miR-99a-5p | −1.188 | 0.001 | −1.324 | 0.03 | 0.006 |
| miR-365a-3p | −1.752 | 0.002 | −1.39 | 0.003 | 0.013 |
| miR-200c-3p | 0.493 | 0.012 | 0.766 | 0.04 | 0.012 |
Log2FC: Logarithm to the base 2 of fold-change; NGS: Next-generation sequencing; qPCR: Quantitative polymerase chain reaction.