Figure 3.

Graphical representation of m6A RNA modification. Adenosine is methylated in position N6 to form m6A by a class of enzymes globally called “writers” and demethylated by a class of enzymes called “erasers.” The two classes of enzymes work together to balance the level of m6A. The m6A message is interpreted by another class of enzymes called “readers” and plays an important role in regulating gene expression by fine modulating different aspects (processing, stability, translation etc.) of RNA molecules.