Table 1.
Disease | Brain Area | Single Site Analysis | Edited Isoform | Reference |
---|---|---|---|---|
MDD | FC | not altered (sites A, C, D) | nd | [40] |
Suicide victims (SCZ and MDD) | FC | ↑ A, = C, ↑ D (trend) | nd | [40] |
MDD | FC | = A, ↑ D (trend) | nd | [41] |
Suicide victims (MDD) | FC | = A, = B,↑ E, ↓ D, ↑ C (trend) | ↑ VGI, ↓ VNI | [42] |
MDD | Cortex | ↓ E, ↓ D, ↓ C (all trend) | not altered | [43] |
Suicide victims (MDD) | PFC | nd | ↑VSV | [45] |
Suicide victims (MDD) | ACC | nd | ↑VNI ↓INV↑ VDV | [46] |
Suicide victims (MDD) | FC | nd | ↑ VNI | [46] |
MDD: Major Depressive Disorder; SCZ: schizophrenia; FC: frontal cortex; PFC: prefrontal cortex; ACC: anterior cingulate cortex; nd: not determined.