Proinflammatory and anti-inflammatory growth factors and chemoattractant mediators in the homogenates of lung tissue. (A) Proinflammatory mediators IFNγ, IL-1β, and IL-6. (B) Anti-inflammatory cytokines IL-10, IL-13, and IL-17α. (C) Growth factors GM-CSF and VEGF and monocyte chemoattractant chemokine MCP1. GM-CSF was not detected (ND) in any of the three control groups; for the statistical analysis, the ND value was used as the detection limit concentration. Data are representative from 2 independent experiments (n = 5–6 per group; mean ± SEM). One-way ANOVA followed by a Newman–Keuls multiple-comparison test was used to evaluate the significant differences * p < 0.01 vs. the corresponding control group (no differences among the three controls groups were observed in any parameter evaluated); # p < 0.01 vs. the HCl + LPS group.