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. 2020 Jul 28;12(8):2100. doi: 10.3390/cancers12082100

Figure 3.

Figure 3

Elevated blood cell counts (BCC) in JAK2V617F and CALR mutation positives in the general population. Deep molecular screening on 19,958 individuals of the 21,205 total from the Danish General Suburban Population Study (GESUS) cohort, revealing 645 to be positive for JAK2V617F (N = 613) or CALR type 1 and type 2 (N = 32). Normal BCC was found in 44% (N = 287), 41% (N = 262) had elevated BCC including hematocrit, erythrocytes, leukocytes, and platelets, whereas 12% (N = 80) had elevated BCC counts fulfilling WHO MPN criteria and 2.5% (N = 16) were already known patients with an MPN diagnosis.