| DM | diabetes mellitus |
| CVD | cardiovascular disease |
| IL | interleukin |
| NLR | NOD-like receptor |
| ADC | Apoptosis-associated speck-like protein containing a CARD |
| NLRPs | NLR proteins |
| HIN | interferon-inducible nature, and nuclear localization |
| AIM2 | absent in melanoma 2 |
| IFI16 | interferon γ-inducible protein 16 |
| NLRP3 | NACHT, LRR and PYD domains-containing protein 3 |
| TLRs | toll-like receptors |
| PRRs | pattern recognition receptors |
| PAMPS | pathogen- associated molecular patterns |
| DAMPs | damage-associated molecular patterns |
| NF-κB | nuclear factor-κB |
| ATP | adenosine triphosphate |
| ROS | reactive oxygen species |
| AGEs | advanced glycation end-products |
| FFAs | free fatty acids |
| MACEs | major adverse cardiovascular events |
| CANTOS | Canakinumab Anti-Inflammatory Thrombosis Outcomes Study |
| GLP | Glucagon-like peptide |
| SGLT | sodium glucose cotransporter |
| hsCRP | high-sensitivity C-reactive protein |
| CIRT | Cardiovascular Inflammation Reduction Trial |
| OxLDLs | oxidized LDLs |
| RAGE | receptor of AGEs |
| SREBP | sterol regulatory element binding protein |
| NETs | neutrophil extracellular traps |
| Foxp1 | forkhead box P transcription factor 1 |
| DKD | diabetic kidney disease |
| ESKD | end-stage kidney disease |
| GFR | glomerular filtration rate |
| RAS | renin-angiotensin system |
| KRIS | kidney risk inflammatory signature |
| TNF | tumor necrosis factor |
| BM | bone marrow |
| TXNIP | Thioredoxin Interacting Protein |
| PR2X7 | purinergic receptor 2X7 |
| DPP | dipeptidyl peptidase |
| DR | diabetic retinopathy |
| PDR | proliferative DR |
| STZ | streptozotocin |
| TRX1 | thioredoxin |
| ALEs | advanced lipoxidation endproducts |
| PGE2 | Prostaglandin E2 |
| EP2R | E-prostanoid receptor |
| PPARα | peroxisome proliferator-activated receptor-α |
| NAFLD | nonalcoholic fatty liver disease |
| NASH | nonalcoholic steatohepatitis |