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. 2020 Aug 3;9(8):2495. doi: 10.3390/jcm9082495

Table 1.

Results for the assessment of thyroid lesions using S-Detect only, the European Thyroid Imaging Reporting and Data System (EU-TIRADS) scale (4 and 5 points), and the mixed MODELs 1 to 5.

Sensitivity Specificity PPV NPV Accuracy
Groups Value 95% CI Value 95% CI Value 95% CI Value 95% CI Value 95% CI
S-Detect 89.4 79.4–95.6 80.6 69.1–89.2 81.9 73.5–88.2 88.5 79.1–94.0 85.0 77.7–90.6
EU-TIRADS (4 and 5 points) 90.9 81.3–96.6 61.2 48.5–72.9 69.8 62.9–75.9 87.2 75.7–93.8 75.9 67.8–82.9
EU-TIRADS (5 points) 80.0 68.7–88.6 79.4 67.9–88.3 80.0 71.2–86.6 79.4 70.4–86.2 79.7 72.0–86.1
MODEL 1 84.9 73–92.5 88.1 77.8–94.7 87.5 78.4–93.1 85.5 76.8–91.3 86.5 79.5–91.8
MODEL 2 95.5 87.3–99.1 53.7 41.1–66.0 67.0 61.0–72.6 92.3 79.5–97.4 74.4 66.2–81.6
MODEL 3 93.9 85.2–98.3 73.1 60.9–83.2 77.5 69.8–83.7 92.5 82.4–97.0 83.5 76.0–89.3
MODEL 4 78.9 67.0–87.9 89.6 79.7–95.7 88.1 78.5–93.8 81.1 72.8–87.3 84.2 76.9–90.0
MODEL 5 93.9 85.2–98.3 80.6 69.1–89.2 82.7 74.5–88.6 93.1 83.8–97.2 87.2 80.3–92.4

CI, confidence interval; PPV, positive predictive value; NPV, negative predictive value; EU-TIRADS, European Thyroid Imaging Reporting and Data System.