Table 3.
Comparison of diagnostic performance of the computer-aided diagnosis (CAD) system and experienced staff.
| Number of Patients | Number of Nodules | Sensitivity (%) | Specificity (%) | PPV (%) | NPV (%) | Accuracy (%) | ||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| CAD | Staff | CAD | Staff | CAD | Staff | CAD | Staff | CAD | Staff | |||
| Current study *, ** | 88 | 133 | 89.4 | 90.9 | 80.6 | 61.2 | 81.9 | 69.8 | 88.5 | 87.2 | 85.0 | 75.9 |
| Gitto S et al. |
62 | 62 | 21.4 | 78.6 | 81.3 | 66.7 | 25.0 | 40.7 | 78 | 91.4 | 67.7 | 69.4 |
| Kim HL et al. * |
106 | 218 | 81.4 | 84.9 | 68.2 | 96.2 | 62.5 | 93.6 | 84.9 | 90.7 | 73.4 | 91.7 |
| Jeong EY et al. |
85 | 100 | 88.6 | 84.1 | 83.9 | 96.4 | 81.3 | 94.9 | 90.4 | 88.5 | 86.0 | 91.0 |
| Chung SR et al. ** |
197 | 197 | 92.0 | 84.0 | 87.9 | 97.9 | 57.5 | 87.5 | 98.4 | 97.2 | 88.5 | 95.8 |
| Park VY et al. |
265 | 286 | 90.4–91.0 | 94.2 | 58.5–80.0 | 76.9 | 72.3–84.5 | 83.1 | 83.5–88.1 | 91.7 | 75.9–86.0 | 86.4 |
| Choi YJ et al. |
89 | 102 | 90.7 | 88.4 | 74.6 | 94.9 | 72.2 | 92.7 | 91.7 | 91.8 | 81.4 | 92.2 |
| Xia S et al. |
171 | 180 | 90.5 | 81.1 | 41.2 | 88.5 | 63.2 | 6.7 | 79.5 | 95.9 | 67.2 | 60.9 |
* CAD, only S-Detect 2 was taken into account. ** Staff with ≥7 years of experience. CAD, computer-aided diagnosis; PPV, positive predictive value; NPV, negative predictive value.