Table 2.
Gene Category | Gene Symbol |
GNP Size (nm) |
Ligand | Fold Change |
Reference |
---|---|---|---|---|---|
Cell cycle | CCNB | 20 | FBS | 0.63 | [94] |
CDH1 | 30 | - | 23 | [95] | |
45 | BSA | 2.22 | [96] | ||
CDKN2B | 1.4 | TTPMS | [77] | ||
CDKN2C | 1.4 | TTPMS | [77] | ||
FBX04 | 1.4 | TTPMS | [77] | ||
HsT17299 | 20 | FBS | 0.57 | [94] | |
MAD2 | 20 | FBS | 0.54 | [94] | |
MCM2 | 20 | citrate | [97] | ||
MCM5 | 20 | citrate | [97] | ||
45 | BSA | 0.59 | [96] | ||
MCM6 | 20 | citrate | [97] | ||
MEF2C | 1.4 | TTPMS | [77] | ||
RPA1 | 2 | MES | [98] | ||
SESN1 | 2 | TMAT | [98] | ||
Cell death (apoptosis) | CASP3 | 15 | citrate | 1.4 | [99] |
CASP7 | 15 | citrate | 1.5 | [99] | |
MCL1 | 18 | citrate | 1.56 | [100] | |
Cell proliferation | ACTG1 | 20 | citrate | [97] | |
ACTN1 | 20 | citrate | [97] | ||
ICAM-1 | 5 | citrate | 0.65 | [101] | |
MMP-9 | 5 | citrate | 0.37 | [101] | |
PIP5K2B | 20 | citrate | [97] | ||
TUBB2A | 20 | citrate | [97] | ||
DNA damage signaling | APEX1 | 2 | MES | [98] | |
ATLD/HNGS1 | 20 | FBS | 0.92 | [94] | |
ATM | 2 | TMAT | [98] | ||
AT-V1/AT-V2 | 20 | FBS | 0.81 | [94] | |
BRCA1 | 20 | FBS | 0.65 | [94] | |
CHEK2 | 18 | PAA | 1.03 | [100] | |
Hus1 | 20 | FBS | 0.85 | [94] | |
MRE11A | 2 | TMAT | [98] | ||
MSH3 | 2 | MES | [98] | ||
RAD9A | 18 | PAA | 1.09 | [100] | |
RAD21 | 2 | TMAT | [98] | ||
RAD51 | 2 | MEEE | [98] | ||
RBBP8 | 20 | FBS | 0.75 | [94] | |
REV1 | 2 | MES | [98] | ||
Oxidative stress | FOSL1 | 1.4 | TTPMS | 8.2 | [77] |
FTH1 | 18 | citrate | 1.52 | [100] | |
GSTM3 | 1.4 | TTPMS | 2.1 | [77] | |
HMOX1 | 1.4 | TTPMS | 23.7 | [77] | |
JUNB | 20 | citrate | [97] | ||
MT1X | 20 | citrate | [97] | ||
NF1X | 20 | citrate | [97] | ||
OSG1N1 | 1.4 | TTPMS | 10.2 | [77] | |
PRDX1 | 18 | citrate | 1.64 | [100] | |
SOD3 | 20 | citrate | [97] |
FBS = fetal bovine serum; BSA = bovine serum albumin, TTPMS = tri-phenylphosphine monosulfonate; MEEE = mercapto-ethoxy-ethoxy-ethanol; MES = mercapto-ethane-sulfonate; TMAT = tri-methyl-ammonium-ethane-thiol.