Table 3.
Correlation between eIF4G Expression and Clinicopathological Characteristics in HCC Patients.
| Characteristic | Group | eIF4G High Expression | eIF4G Low Expression | p Value |
|---|---|---|---|---|
| Gender | Male | 13 | 3 | 0.6300 |
| Female | 6 | 3 | ||
| Age (years) | <50 | 1 | 2 | 0.1326 |
| ≥50 | 18 | 4 | ||
| AFP (ng/mL) | <400 | 11 | 6 | 0.1292 |
| ≥400 | 8 | 0 | ||
| Etiology | Hepatitis B | 1 | 1 | 0.0812 |
| Hepatitis C | 7 | 0 | ||
| Alcohol | 6 | 0 | ||
| NASH | 1 | 1 | ||
| Autoimmune | 0 | 1 | ||
| Vinyl chloride | 1 | 0 | ||
| Colorectal metastasis | 0 | 1 | ||
| Unknown | 3 | 2 | ||
| Liver cirrhosis | Present | 10 | 2 | 0.6447 |
| Absent | 9 | 4 | ||
| Tumor size (cm) | <5 | 13 | 4 | >0.9999 |
| ≥5 | 6 | 2 | ||
| Tumor number | Single | 13 | 6 | 0.2778 |
| Multiple | 6 | 0 | ||
| Edmondson-Steiner grade | G1 | 0 | 1 | 0.0694 |
| G2 | 10 | 4 | ||
| G3 | 9 | 1 | ||
| ECGO PS | 0 | 18 | 5 | 0.4300 |
| 1 | 1 | 1 | ||
| Child-Pugh class | A | 19 | 5 | 0.2400 |
| B | 0 | 1 | ||
| BCLC stage | 0 + A | 15 | 5 | >0.9999 |
| B | 4 | 1 | ||
| TNM stage | I + II | 11 | 5 | 0.3644 |
| III | 8 | 1 | ||
| Recurrence | Positive | 10 | 2 | 0.6447 |
| Negative | 9 | 4 | ||
| Recurrence Pattern | Intrahepatic only | 9 | 0 | 0.0271 * |
| n = 12 | Extrahepatic only | 0 | 1 | |
| Both | 1 | 1 | ||
| Ki-67 expression | High | 9 | 2 | 0.6609 |
| Low | 10 | 4 | ||
| Midkine expression | High | 12 | 3 | 0.6532 |
| Low | 7 | 3 | ||
| Patient survival (%) | 1-year OS | 75.89 | 100 | >0.9999 |
| 1-year PFS | 41.32 | 80 | 0.0953 | |
| 3-year OS | 38.55 | 100 | 0.1861 | |
| 3-year PFS | 27.55 | 80 | 0.2774 | |
| 5-year OS | 0 | 100 | 0.1753 | |
| 5-year PFS | 0 | 80 | 0.2335 |
Abbreviations: *, p < 0.05.