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. 2020 Aug 17;25(16):3744. doi: 10.3390/molecules25163744

Table 3.

Antibacterial activity of compounds isolated from Pseudomonas aeruginosa UWI-1.

Minimum Inhibitory Concentration/Minimum Cidal Concentration (µg mL−1)
Gram Positive Gram Negative
Rods Cocci Rods Cocci
Compound Bacillus Cereus Listeria Monocytogenes Corynebacterium Diphtheria MR-Staphylococcus Aureus Streptococcus Pyogenes Escherichia Coli Salmonella Enteritidis Klebsiella Oxytoca Neisseria Meningitides Haemophilus Influenza
1 4/4 8/8 16/32 2/4 1/2 32/128 64/128 128/>512 32/32 32/32
2 64/128 128/256 32/64 32/32 64/64 NI NI NI NI NI
3 2/16 4/16 16/64 2/4 1/16 32/128 2/4 16/32 4/16 1/2
Kanamycin 32/32 64/64 128/NI 128/128 256/NI 4/4 8/16 4/16 16/16 32/32
Erythromycin <1/2 4/4 NI 2/2 32/64 256/256 NI NI NI 128/128

NI; No inhibition observed at the concentrations tested (512–1 µg mL−1). Antibacterial activity was determined using the broth microdilution assay to determine the minimum inhibitory concentration (MIC) of the test compounds. Minimum bactericidal concentration (MBC) was assessed by plating samples from wells with negative growth in the MIC determination assay. Values represent the average MIC/MBC of three replicates (n = 3). In each case no deviation was observed and therefore the SD = ± 0.0. Kanamycin was used as a Gram-negative positive control and Erythromycin was used as a Gram-positive positive control in this study.