Table 2.

Adjusted hazard ratios (HRs) of overall survival of gastric cancer patients after surgery and adjuvant chemotherapy associated with statin use after surgery during the follow-up period in the matched cohort.

Variables	28–167 cDDD				≥168 cDDD
	HR	95% CI		p-Value	HR	95% CI		p-Value
Main Model *	0.62	0.50	0.78	<0.0001	0.34	0.26	0.45	<0.0001
Additional Covariates †
Main model + Diabetes mellitus	0.64	0.51	0.80	<0.0001	0.33	0.25	0.44	<0.0001
Main model + Hypertension	0.62	0.50	0.78	<0.0001	0.34	0.26	0.45	<0.0001
Main model + Alcoholism	0.62	0.50	0.78	<0.0001	0.34	0.26	0.45	<0.0001
Main model + Smoking-related disorder	0.62	0.50	0.78	<0.0001	0.34	0.26	0.45	<0.0001
Main model + Chronic renal failure	0.62	0.50	0.78	<0.0001	0.34	0.26	0.45	<0.0001
Main model + Liver cirrhosis	0.62	0.50	0.77	<0.0001	0.34	0.26	0.45	<0.0001
Main model + Chemotherapy regimen	0.63	0.50	0.78	<0.0001	0.33	0.25	0.44	<0.0001
Main model + Triglyceride-lowering drugs	0.62	0.50	0.78	<0.0001	0.35	0.26	0.46	<0.0001
Main model + Non-statin lipid-lowering drugs	0.62	0.50	0.78	<0.0001	0.34	0.26	0.45	<0.0001
Main model + ACE inhibitors	0.61	0.49	0.76	<0.0001	0.34	0.26	0.45	<0.0001
Main model + Aspirin	0.60	0.48	0.75	<0.0001	0.33	0.25	0.44	<0.0001
Main model + NSAID	0.60	0.48	0.75	<0.0001	0.32	0.24	0.43	<0.0001
Subgroup Effects
Sex
Male	0.76	0.57	1.02	0.0674	0.41	0.30	0.57	<0.0001
Female	0.49	0.35	0.70	<0.0001	0.23	0.14	0.40	<0.0001
Age at Surgery
18–64	0.46	0.31	0.67	<0.0001	0.24	0.14	0.41	<0.0001
≥65	0.75	0.57	0.99	0.0402	0.40	0.29	0.55	<0.0001

* Main model was adjusted for sex, age, urbanization, and income. ^† The models were adjusted for covariates in the main model as well as each additional listed covariate.