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. 2020 Aug 14;12(8):2279. doi: 10.3390/cancers12082279

Figure 4.

Figure 4

Transmission electron microscopy demonstrates ultrastructural features of S2VP10 cells treated with echinomycin. (A) Autophagosomes (#) are visible. (B) Joining of autophagosome with the lysosome (autolysosome *). (C) Plasma and nuclear membranes are intact and lack of significant changes in chromatin structure. Approximately 35% of cytoplasmic space observed contains large vacuoles.