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. 2020 Aug 8;10(8):531. doi: 10.3390/brainsci10080531

Table 4.

Partial parameters, paradigm and results of tES effect speech understanding studies.

Reference Sample Size Stimulation Types Stimulation
Electrode
Position and Size
Reference Electrode
Position and Size
Stimulation
Parameters
The Number of Stimulation Sessions Auditory Paradigm TACS Time Lags TACS Phase Relationships Results
Wilsch, et al., 2018 [102] 19 Envelope—tACS/sham Simultaneous
Cz (35 cm2) T3 and T4 (4.18 × 4.18 cm)
Unspecified between 0.4 mA–1.5 mA
unspecified time
Two stimulation sessions Oldenburg sentence test 0–250 ms, in 50-ms steps Unspecified The sinusoidal fit with an average frequency of 5.12 Hz has a good effect on envelope-tACS modulation of speech intelligibility
Zoefel, et al., 2020 [103] Group 1: n = 27
Group 2: n = 19
Group 1: unilateral tACS and sham
Group 2: bilateral tACS and sham
Group 1: T7 (3 × 3 cm) C3 (5 × 7cm).
Group 2: T7 and T8 doughnut-shaped electrodes inner ring (d 1 = 2 cm, t 2 = 0.1 cm) external ring (outer d 1 = 10 cm, inner d 1 = 7.5 cm, t 2 = 0.2 cm)
Unspecified Group 1: 1.7 mA
Group 2: 1.2 mA
unspecified time
Two stimulation sessions Speech comprehension test (rhythmic noise-vocoded speech) 0–280 ms, in 40-ms steps 0–7π/4, in steps of π/4 Modulation of speech perception induced by tACS in the case of bilateral stimulation using ring electrodes
Kadir, et al., 2020 [105] 17 Envelope—tACS/sham Simultaneous
T7 and T8 (35 cm2)
Either side of the Cz (35 cm2) between 0.2–1.5 mA
unspecified time
Two stimulation sessions Speech comprehension test (SRT assessment) Fixed lag times of 100 ms and 250 ms 0–5π/3, in steps of π/3 Between a short latency of 100 ms and a long latency of 250 ms, the modulation of speech understanding by the phase of the stimulus was different
Keshavarzi, et al., 2020 [106] 18 Envelope—tACS/sham Simultaneous
T7 and T8 (35 cm2)
Either side of the Cz (35 cm2) between 0.7 mA-1.3 mA
unspecified time
Two stimulation sessions Speech comprehension test (SRT assessment) Unspecified 0–5π/3, in steps of π/3 The tACS effect speech understanding in the θ band, had no effect on speech understanding in the δ band
Compared with the sham stimulation, the current stimulation in the θ band can improve the understanding of speech in noise

1 d, diameter; 2 t, thickness.