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Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
Breast tumor microenvironment (TME). Interaction among breast cancer cells and different processes involved in tumor microenvironment development. These include angiogenesis, tumor metastasis, ECM degradation and remodeling, cytokines and chemokines release, hypoxia, and VEGF release.