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. 2020 Jul 22;9(8):2342. doi: 10.3390/jcm9082342

Figure 1.

Figure 1

Uracil and 5-fluorouracil degradation pathway. Uracil and 5-fluorouracil are catabolized successively by dihydropyrimidine dehydrogenase, dihydropyrimidinase, and β-ureidopropionase. β-Alanine and fluoro-β-alanine are the final metabolites in this pathway.