Figure 3.

Effects of cashew nuts on nitrate/nitrite, MPO, and MDA activity after CAR-injection. As a consequence of neutrophils infiltration and lipid peroxidation MPO and MDA were assessed. Additionally, considering the key role played by NO during inflammatory events, we analyzed also levels in nitrite/nitrate in paw exudate. Carrageenan induces a significant increase in all parameter taken in consideration. On the other hands, oral treatment with cashew nuts at the dose of 100 mg/kg significantly reduced MPO, MDA, and nitrate/nitrite CAR-induction. MPO (A); MDA (B); nitrate/nitrite (C). See materials and methods for further details. # p < 0.05 vs. CAR; ## p < 0.01 vs. CAR; *** p < 0.001 vs. sham.