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. 2020 Aug 1;202(3):412–421. doi: 10.1164/rccm.201910-1926OC

Table 1.

Selected Study Population Characteristics by Lung Cancer Status and Silica Exposure

Characteristic Ever Exposed to Silica
Never Exposed to Silica
Cases (n) % Control Subjects (n) % Cases (n) % Control Subjects (n) %
Sex                
 M 4,649 94.4   4,140 92.2 8,956 74.8 12,311 74.7
 F 274 5.6   348 7.8 3,022 25.2 4,166 25.3
Age group                  
 <45 yr 142 2.9   194 4.3 573 4.8 1,177 7.1
 45–64 yr 2,503 50.8   2,055 45.8 6,260 52.3 8,299 50.4
 >64 yr 2,278 46.3   2,239 49.9 5,145 43.0 7,001 42.5
Smoking status                  
 Never-smoker 248 5.0   1,253 27.9 1,121 9.4 5,900 35.8
 Former smoker 1,736 35.3   2,010 44.8 3,696 30.9 6,210 37.7
 Current smoker 2,939 59.7   1,225 27.3 7,161 59.8 4,367 26.5
Smoking pack-years                  
 Never-smoker 248 5.0   1,253 27.9 1,121 9.4 5,900 35.8
 <10 227 4.6   683 15.2 582 4.9 2,386 14.5
 10–19 475 9.6   598 13.3 1,127 9.4 2,264 13.7
 >19 3,973 80.7   1,954 43.5 9,148 76.4 5,927 36.0
Years since quitting smoking                  
 Never-smoker 248 5.0   1,253 27.9 1,121 9.4 5,900 35.8
 >0–7 yr 638 13.0   317 7.1 1,388 11.6 1,105 6.7
 8–15 yr 494 10.0   461 10.3 1,037 8.7 1,437 8.7
 16–25 yr 379 7.7   590 13.1 792 6.6 1,756 10.7
 >25 yr 225 4.6   642 14.3 479 4.0 1,912 11.6
 Current smoker 2,939 59.7   1,225 27.3 7,161 59.8 4,367 26.5
List A job                  
 Ever employment 829 16.8   597 13.3 958 8.0 767 4.7
 Never employment 4,094 83.2   3,891 86.7 10,905 92.0 15,563 95.3
Silicosis                  
 Reported silicosis 57 1.2   33 0.7 13 0.1 5 0
 No reported silicosis 2,882 58.5   2,311 51.5 6,091 50.9 7,539 45.8
 Unknown 1,984 40.3   2,144 47.8 5,874 49.0 8,933 54.2
Lung cancer subtype                  
 Adenocarcinoma 1,069 21.7   3,683 30.7
 Small cell carcinoma 869 17.7   1,861 15.5
 Squamous cell carcinoma 2,251 45.7   4,252 35.5
 Other/unspecified 711 14.4   2,111 17.6
 Not available 23 0.5   71 0.6