| 3CLpro | 3C-like protease |
| CoV | coronavirus |
| COVID-19 | coronavirus disease 2019 |
| C-term | C-terminal |
| FLuc | firefly luciferase |
| HAE | human airway epithelial |
| HCV | hepatitis C virus |
| HDV | hepatitis delta virus |
| HIV | human immunodeficiency virus |
| HSV | herpes simplex virus |
| HTS | high-throughput screening |
| IRES | internal ribosome entry site |
| MERS | Middle East respiratory syndrome |
| MHV | mouse hepatitis virus |
| NLuc | Nano-glo® luciferase |
| NSP | nonstructural proteins |
| N-term | N-terminal |
| PLpro | papain-like protease |
| RdRp | RNA-dependent RNA polymerase |
| SARI | severe acute respiratory infection |
| SARS | severe acute respiratory syndrome |
| UTR | untranslated region |