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. 2020 Aug 1;9(8):201. doi: 10.3390/biology9080201

Figure 6.

Figure 6

(A) Barplot showing the alteration frequency of all hub genes (9.24% of 660 cases of LUAD and 9.71% of 484 cases of LUSC) across TCGA Pan-NSCLC dataset. Green bars represent frequency of mutations (5% in LUAD and 3.93% in LUSC), red bars represent frequency of amplifications (2.27% in LUAD and 2.69% in LUSC), blue bars represent frequency of deep deletion (1.67% in LUAD and 2.89% in LUSC), and grey bars represent frequency of multiple alterations (0.3% in LUAD and 0.2% in LUSC). (B) Boxplot showing alteration frequency of 2 TFs—HMGA2 and E2F7—with overall frequency of 6% (8.04% of 660 cases of LUAD and 3.93% of 484 cases of LUSC) in the selected NSCLC dataset. Green bars represent frequency of mutations (3.79% in LUAD and 2.27% in LUSC), red bars represent frequency of amplifications (3.94% in LUAD and 1.65% in LUSC), blue bars represent frequency of deep deletion (0.15% in LUAD), and grey bars represent frequency of multiple alterations (0.15% in LUAD).