Table 4.

Top 10 hub genes according to the out-degree centrality from our proposed method.

Gene Symbol	In-Degree	Out-Degree	Average Shortest Path Length	Betweenness Centrality	Closeness Centrality	Clustering Coefficient
$\mathit{MRPL}\mathit{35}$	239	376	2.765	9.354	0.362	0.141
$\mathit{FAM}\mathit{177}\mathit{A}\mathit{1}$	21	339	3.002	0.263	0.333	0.225
$\mathit{STAT}\mathit{4}$	94	332	2.872	2.744	0.348	0.211
$\mathit{ASPSCR}\mathit{1}$	68	329	2.888	1.132	0.346	0.212
$\mathit{FABP}\mathit{7}$	204	315	2.779	3.008	0.360	0.171
$\mathit{HNRNPA}\mathit{0}$	65	311	3.010	1.230	0.332	0.191
$\mathit{ANGPTL}\mathit{4}$	18	299	2.887	0.364	0.346	0.249
$\mathit{DDX}\mathit{19}\mathit{A}$	86	283	2.993	1.385	0.334	0.218
$\mathit{TRNT}\mathit{1}$	40	282	3.119	0.477	0.321	0.221
$\mathit{PFDN}\mathit{1}$	52	274	3.005	0.526	0.333	0.243