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. 2020 Jul 28;12(8):2091. doi: 10.3390/cancers12082091

Figure 1.

Figure 1

PRMT5 expression is shown to be upregulated, as well as positively correlated with KRAS expression, in CRC patient datasets. (a) RNA-Seq data of CRC patients from the TCGA database using the GEPIA website showing that PRMT5 is overexpressed (q < 0.01) in CRC patient tumor samples when compared to normal colon and rectum tissue; (b) RNA-Seq data of CRC patients from the TCGA database using the GEPIA website displaying that PRMT5 expression is strongly positively correlated (p < 0.005, R = 0.81) with KRAS expression in CRC patient tumor samples.