Table 2.
Longitudinal associations between Ferric Reducing Ability of Plasma (FRAP) score and fat mass index, fat-free mass index, android-to-gynoid fat ratio, body mass index and body fat percentage.
| Fat Mass Index (kg/m2) | p-Value | Fat-Free Mass Index (kg/m2) | p-Value | Android-To-Gynoid Fat Ratio | p-Value | Body Mass Index (kg/m2) | p-Value | Body Fat % | p-Value | |
|---|---|---|---|---|---|---|---|---|---|---|
| Model 1 a | −0.083 (−0.156; −0.010) |
0.026 | 0.076 (0.016; 0.135) |
0.013 | −0.028 (−0.054; −0.002) |
0.033 | 0.039 (−0.058; 0.137) |
0.426 | −0.365 (−0.527; −0.202) |
<0.001 |
| Model 2 b | −0.037 (−0.108; 0.033) |
0.301 | 0.088 (0.028; 0.147) |
0.004 | −0.029 (−0.054; −0.004) |
0.025 | 0.092 (−0.002; 0.186) |
0.055 | −0.266 (−0.425; −0.107) |
0.001 |
| Model 3 c | −0.018 (−0.089; 0.053) |
0.619 | 0.091 (0.031; 0.150) |
0.003 | −0.028 (−0.053; −0.003) |
0.026 | 0.115 (0.020; 0.209) |
0.017 | −0.223 (−0.383; −0.064) |
0.006 |
N = 4595. Results are presented as regression coefficient (β) with corresponding 95% CI per 1 standard deviation increment in FRAP. a Model 1: adjusted for time interval, age, sex and Rotterdam Study cohort. b Model 2: additionally adjusted for hypertension status, presence of dyslipidemia, daily alcohol consumption, daily physical activity, smoking status, highest attained level of education and serum glucose. c Model 3: additionally adjusted for adherence to dietary guideline score. At the baseline examination round (cohorts RS-I-5, II-2 and III-1), 3770 participants underwent a DXA measurement; during the second round (cohorts I-6, II-3 and III-2), 3492 participants were measured and, during the final examination round (cohort II-4), 718 participants were measured. Of the 4595 total participants, 1530 participants were measured once during the study period, 2705 were measured twice and 360 were measured at all three time points.