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. 2020 Aug 10;9(8):2586. doi: 10.3390/jcm9082586

Table 3.

Day-7 mortality and time to discharge. Multivariable analysis.

Adjusted Odds Ratio (OR) Adjusted Hazard Ratio (aHR) &
(n = 1158) (n = 1167)
aOR, (95% CI) p-Value aHR, (95% CI) p-Value
NSAID 0.79 (0.32–1.92) 0.602 0.89 (0.59–1.35) 0.58
Age
   Under 65 -Ref- -Ref-
   65 to 79 3.80 (2.26–6.37) <0.001 0.76 (0.61–0.95) 0.02
   Over 80 5.14 (3.04–8.69) <0.001 0.56 (0.44–0.73) <0.001
Sex
   Female -Ref- -Ref-
   Male 0.81 (0.57–1.14) 0.227 0.92 (0.76–1.11) 0.37
Smoking status
   Never
   Ex-smokers 1.17 (0.83–1.67) 0.372 0.95 (0.78–1.15) 0.61
   Current smokers 1.12 (0.54–2.33) 0.765 1.04 (0.73–1.48) 0.84
Elevated CRP (>40) 4.91 (2.99–8.06) <0.001 0.69 (0.57–0.84) <0.001
Patients with diabetes 1.04 (0.71–1.52) 0.838 0.84 (0.68–1.04) 0.12
Patients with CAD 1.46 (1.00–2.13) 0.051 1.12 (0.88–1.42) 0.36
Patients with hypertension 0.78 (0.55–1.10) 0.157 0.95 (0.79–1.16) 0.63
Patients with reduced renal function (eGFR < 60) 2.02 (1.42–2.86) <0.001 0.92 (0.75–1.13) 0.58

& The multivariable mixed-effects analysis was adjusted for age group, sex, smoking, CRP level, diabetes, CAD, hypertension and renal function.