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Effect of IQGAP3 on cellular morphology, motility, and invasion. (A) Morphological change of 293T cells by exogenous IQGAP3 expression. (B) Representative pictures of the wound-healing assay using NIH3T3 cells expressing IQGAP3 (NIH3T3-IQGAP3) and control (NIH3T3-mock) cells. (C) Effect of IQGAP3 on cell invasion by Matrigel assay. The relative number of invading NIH3T3-IQGAP3 cells was compared with control (NIH3T3-mock) cells (* p < 0.01; two-tailed Student’s t-test).
