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ANXA8 overexpression due to RA-RARA downregulation of ANXA8-regulatory miRNAs. (A) RA via RARA regulates ANXA8 regulatory miRNAs targeting the 3′untranslated region (3′UTR) of ANXA8 mRNA. (B) Factors inhibiting the RA-RARA regulation of ANXA8-regulatory miRNAs induce ANXA8 protein upregulation.
