Table 3.
Comparison of QLQ-C30 score according to sensory CIPN and correlation between QLQ-C30 score and QLQ-CIPN20 sensory score. The correlations between the QLQ-C30 score and QLQ-CIPN20 sensory score are presented with the correlation coefficient and significance.
| Dimensions | QLQ-C30 Scores |
QLQ-C30 Scores According to Sensory CIPN | Correlations QLQ-C30 and Sensory Scores |
||
|---|---|---|---|---|---|
| No Sensory CIPN |
Sensory CIPN |
Effect Size (95% CI) |
|||
| Global health status | 69.2 ± 20.5 | 71.6 ± 20.1 | 63.7 ± 20.4 *** | −0.39 (−0.61, −0.18) | −0.28 # |
| Physical functioning | 81.7 ± 19.7 | 84.7 ± 17.8 | 75.0 ± 22.1 *** | −0.50 (−0.71, −0.29) | −0.32 # |
| Role functioning | 79.1 ± 28.2 | 84.2 ± 24.5 | 67.9 ± 32.3 *** | −0.60 (−0.81, −0.38) | −0.38 # |
| Emotional functioning | 74.6 ± 25.1 | 78.8 ± 22.5 | 65.2 ± 27.8 *** | −0.56 (−0.77, −0.34) | −0.32 # |
| Cognitive functioning | 77.6 ± 23.5 | 80.7 ± 21.0 | 70.7 ± 27.2 *** | −0.43 (−0.64, −0.22) | −0.22 # |
| Social functioning | 74.3 ± 30.5 | 78.6 ± 28.2 | 64.5 ± 33.1 *** | −0.47 (−0.69, −0.26) | −0.28 # |
| Fatigue | 33.7 ± 27.2 | 28.3 ± 24.6 | 45.5 ± 29.0 *** | 0.66 (0.44, 0.87) | 0.36 # |
| Nausea and vomiting | 6.5 ± 15.7 | 5.7 ± 14.8 | 8.4 ± 17.4 | 0.17 (0.04, 0.38) | 0.17 # |
| Pain | 20.5 ± 26.0 | 14.0 ± 22.2 | 34.6 ± 28.1 *** | 0.85 (0.63, 1.07) | 0.42 # |
| Dyspnea | 23.2 ± 28.1 | 21.0 ± 26.6 | 28.0 ± 30.8 * | 0.25 (0.04, 0.46) | 0.18 # |
| Insomnia | 34.8 ± 35.4 | 29.1 ± 33.4 | 47.4 ± 36.4 *** | 0.53 (0.32, 0.74) | 0.28 # |
| Appetite loss | 11.2 ± 23.6 | 8.9 ± 20.6 | 16.4 ± 28.5 ** | 0.32 (0.11, 0.53) | 0.21 # |
| Constipation | 19.3 ± 28.2 | 17.1 ± 26.8 | 24.1 ± 30.9 * | 0.25 (0.04, 0.46) | 0.14 # |
| Diarrhea | 24.2 ± 31.9 | 20.7 ± 29.5 | 31.7 ± 35.5 ** | 0.35 (0.14, 0.56) | 0.23 # |
| Financial difficulties | 9.9 ± 22.2 | 6.9 ± 17.0 | 16.5 ± 29.8 ** | 0.44 (0.23, 0.65) | 0.20 # |
* p < 0.05, ** p < 0.01, and *** p < 0.001 for no sensory CIPN vs. sensory CIPN; # p < 0.05.