ACE |
Angiotensin-converting enzyme |
AGEs |
Advanced glycation endproducts |
AMD |
Age-related macular degeneration |
Ang |
Angiotensin |
ApoE |
Apolipoprotein E |
AREDS |
Age-Related Eye Disease Study |
AR |
Aldose reductase |
AREs |
Antioxidant response elements |
AT1R |
Angiotensin II receptor type 1 |
AT2R |
Angiotensin II receptor type 2 |
A1 |
Arginase 1 |
A2 |
Arginase 2 |
ATP |
Adenosine triphosphate |
BH4 |
Tetrahydrobiopterin |
BH2 |
7,8-dihydrobiopterin |
BRB |
Blood-retinal barrier |
CVD |
Cardiovascular disease |
CRAO |
Central retinal artery occlusion |
DAG |
Diacylglycerol |
DMOG |
Dimethyloxalylglycine |
DR |
Diabetic retinopath |
DUOX1 |
Dual oxidase 1 |
DUOX2 |
Dual oxidase 2 |
ETC |
Electron transport chain |
eNOS |
endothelial nitric oxide synthase |
ERK |
Extracellular signal-related kinase |
FA |
Fenofibric acid |
FH |
Familial hypercholesterolemia |
GCL |
Ganglion cell layer |
GPR91 |
Succinate receptor G protein-coupled receptor-91 |
HO-1 |
Heme oxygenase-1 |
H2O2
|
Hydrogen peroxide |
HO2•
|
Hydroperoxyl |
HOC1 |
Hypochlorous acid |
HIF-1α |
Hypoxia-inducible factor-1α |
ICAM-1 |
Intercellular adhesion molecule-1 |
IL-1α |
Interleukin-1 alpha |
IL-β |
Interleukin-1 beta |
IL-6 |
Interleukin-6 |
IVTA |
Intravitreal injection of triamcinolone acetonide |
I/R |
Ischemia/reperfusion |
iBRB |
Inner blood-retinal barrier |
iNOS |
inducible nitric oxide synthase |
JNK |
c-Jun N-terminal kinase |
KO |
Knockout |
LDL-C |
Low-density lipoprotein cholesterol |
L |
Lutein |
mtROS |
mitochondria-derived ROS |
mtDNA |
mitochondrial DNA |
MCP1 |
Monocyte chemoattractant protein-1 |
MD2 |
Myeloid differentiation protein 2 |
NADPH oxidase |
Nicotinamide adenine dinucleotide phosphate oxidase |
NF-κB |
nuclear factor-kappa B |
NLRP3 |
Pyrin domain-containing 3 |
NMDA |
N-methyl-D-aspartate |
NOX |
NADPH oxidases |
NO |
Nitric oxide |
NOS |
nitric oxide synthase |
nNOS |
neuronal nitric oxide synthase |
NRF2 |
Nuclear factor erythroid-derived 2-related factor 2 |
NTs |
Neurotrophins |
O2•−
|
Superoxide |
O3
|
Ozone |
oBRB |
Outer blood-retinal barrier |
OCT |
Octreotide |
•OH |
Hydroxyl radicals |
ox-LDL |
oxidized-LDL |
ONOO—
|
Peroxynitrite |
PARP |
Poly (ADP-ribose) polymerase |
PCSK9 |
Proprotein convertase subtilisin/kexin type 9 |
PDGF |
Platelet-derived growth factor |
PDGFRβ |
Platelet-derived growth factor receptor beta |
PKC |
Protein kinase C |
PPAR |
Peroxisome proliferator-activated receptor |
RAAS |
Renin-angiotensin-aldosterone system |
RAGE |
Receptors for advanced glycation endproducts |
RAS |
Renin-angiotensin system |
RCS |
Reactive copper species |
RGC |
Retinal ganglion cell |
RIS |
Reactive iron species |
RNS |
Reactive nitrogen species |
ROS |
Reactive oxygen species |
RPE |
Retinal pigment epithelium |
ROO•
|
Peroxyl |
RO•
|
Alkoxyl |
RRMS |
Relapsing-remitting multiple sclerosis |
SIRT1 |
NAD-dependent deacetylase sirtuin1 |
SOD |
Superoxide dismutase |
TAGE |
toxic AGEs |
TLR4 |
Toll-like receptor 4 |
TLR2 |
toll-like receptor 2 |
TNF-α |
Tumor necrosis factor-alpha |
VEGF |
vascular endothelial growth factor |
Z |
Zeaxanthin |
1△g |
Singlet oxygen |