Table 2.
General characteristics of population
| Population N = 99 |
Afatinib N = 40 |
Erlotinib N = 26 |
Gefitinib N = 33 |
|
|---|---|---|---|---|
| Gender | ||||
| ▪ Women | 73 (73.7%) | 28 (70.0%) | 22 (84.6%) | 23 (69.7%) |
| ▪ Men | 26 (26.3%) | 12 (30.0%) | 4 (15.4%) | 10 (30.3%) |
| Age (years) | 61.2 (14.0) | 57.925 (14.5) | 64.3 (12.8) | 62.8 (14.0) |
| Stage IV NSCLC | 83 (83.8) | 33 (82.5) | 22 (84.61) | 28 (84.84) |
| Current or former smoker | 22 (22.2%) | 3 (11.5%) | 4 (12.1%) | 15 (15.2%) |
| Woodsmoke exposure | 16 (16.2%) | 4 (15.4%) | 6 (18.2%) | 16 (16.2%) |
| Karnofsky | ||||
| • 50 | 2 (2.2%) | 1 (2.6%) | 1 (4.2%) | 0 (0.0%) |
| • 60 | 3 (3.2%) | 2 (5.3%) | 0 (0.0%) | 1 (3.2%) |
| • 70 | 12 (12.9%) | 4 (10.5%) | 4 (16.7%) | 4 (12.9%) |
| • 80 | 33 (35.5%) | 14 (36.8%) | 7 (29.2%) | 12 (38.7%) |
| • 90 | 38 (40.9%) | 16 (42.1%) | 12 (50%) | 10 (32.3%) |
| • 100 | 5 (5.4%) | 1 (2.6%) | 0 (0.0%) | 4 (12.9%) |
| • Not Reported | 6 | 2 | 2 | 2 |
| ECOG | ||||
| • 0 | 2 (2.2%) | 0 (0.0%) | 0 (0.0%) | 2 (6.5%) |
| • 1 | 75 (81.5%) | 34 (91.9%) | 18 (75.0%) | 23 (74.2%) |
| • 2 | 12 (13.0%) | 2 (5.4%) | 4 (16.7%) | 6 (19.4%) |
| • 3 | 3 (3.3%) | 1 (2.7%) | 2 (8.3%) | 0 (0.0%) |
| • Not Reported | 7 | 3 | 2 | 2 |
| Diabetes Mellitus | 17 (17.2%) | 5 (12.5%) | 5 (19.2%) | 7 (21.2%) |
| Arterial hypertension | 23 (23.2%) | 8 (20.0%) | 7 (26.9%) | 8 (24.2%) |
| EGFR Mutation | ||||
| ▪ EGFR del 19 | 25 (25.3%) | 12 (30.0%) | 5 (19.2%) | 8 (24.2%) |
| ▪ EGFR L858R | 67 (67.7%) | 27 (67.5%) | 16 (61.5%) | 24 (72.7%) |
| ▪ Non-reported | 7 (7.1% | 1 (2.5%) | 5 (19.2%) | 1 (3.0%) |