Scheme 1.
Reaction mechanism of OGG1. The shown steps are (i) damaged DNA-binding, (ii) oxoG release concerted with Schiff base formation, (iii) β-elimination, (iv) Schiff base hydrolysis, (v) DNA product release.
Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.