Table 1.
Demographic and clinical features of paediatric celiac patients and paediatric controls with nonceliac gastrointestinal disorders
| Demographic and clinical variables | Case (n = 57) (mean [SD]) |
Control (n = 16) (mean [SD]) |
P value |
|---|---|---|---|
| Age (years) | 9.7 (4.3) | 11.2 (4.2) | 0.24 |
| Gender (M:F) (n) | 30:27 | 9:7 | 0.80 |
| Weight (kg) | 35.8 (18.7) | 41.2 (16.7) | 0.36 |
| Height (cm) | 138.2 (26.3) | 139.8 (21.2) | 0.85 |
| BMI (kg/m2) | 18.0 (4.6) | 20.0 (3.6) | 0.16 |
| aTTG (IU) | 354.1 (499.8) | 1.3 (0.9) | 0.023 |
| Biopsies distal (n) | 5.9 (1.1) | 4.1 (1.2) | <0.001 |
| Biopsies bulb (n) | 1.9 (0.5) | 2.0 (0.4) | 0.57 |
| Common Presenting Symptoms* | |||
| Abdominal pain (n) | 34 (59.6%) | 14 (87.5%) | 0.034 |
| Bloating (n) | 18 (31.6%) | 1 (6.3%) | 0.06 |
| Diarrhea (n) | 15 (26.3%) | 5 (31.3%) | 0.49 |
| Vomiting (n) | 4 (7.0%) | 5 (31.3%) | 0.003 |
| Constipation (n) | 17 (29.8%) | 3 (18.8%) | 0.68 |
| Poor weight gain or weight loss (n) | 16 (28.1%) | 3 (18.8%) | 0.36 |
| Asymptomatic (n) | 8 (14.0%) | 1 (6.3%) | 0.28 |
*The number of patients where presenting symptoms were recorded varied; hence, the frequency of symptoms presented above may differ from the true frequencies among the case and control groups.
History (presence or absence) of presenting symptoms was recorded/available for: abdominal pain (91.2% of cases, 93.8% of controls); bloating (80.7% of cases, 62.5% of controls); diarrhea (84.2% of cases, 81.3% of controls); vomiting (80.7% of cases, 75% of controls); constipation (80.7% of cases, 75% of controls); poor weight gain or weight loss (87.7% of cases, 62.5% of controls); asymptomatic (98.2% of cases, 100% of controls).