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. 2020 Jul 22;9(8):2325. doi: 10.3390/jcm9082325

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© 2020 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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The urine QSant assay and Q-Score can help reduce unnecessary renal biopsies. (A) The study cohort contains a total of 163 for-cause biopsies, of which 124 had Q-Scores below the rejection threshold of 32. Of the 60 protocol biopsies, 30 had a score below the rejection threshold of 32. The breakdown of different biopsy diagnoses paired with the sample is shown in the figure as percentages. (B) In this study cohort, if physicians had Q-Scores on hand, the test results would have impacted their decision to not order biopsy for 69% (154/223) of the time. (C) Accuracy of biopsy (for-cause vs. protocol) and the Q-Score (score < 32 vs. score ≥ 32) for classifying AR and STA using Banff classification confirmed biopsies as reference standard.