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. 2020 Jul 28;12(8):2097. doi: 10.3390/cancers12082097

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© 2020 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Comparative effects of OME and TMZ on cell migration, invasion and growth. 15-037 cells were treated with DMSO, 100 µM OME, 500 µM TMZ, and their combination and effects on cell migration (A), invasion in the Boyden chamber (B) and spheroid cell (C) assays and proliferation (D) were determined as outlined in the Materials and Methods. Results are expressed as means ± SD for at least 3 separate determinations for each treatment group and significant (p < 0.05) inhibition by individual compounds (*) and enhanced inhibition by the drug combination (compared to TMZ) (**) are indicated.