Table 1.

Candidate drivers defined in a minimal region using arrays.

Reference	1q Gain	2p Gain	6p Gain	16q Loss	Eye No.	Array
Kooi et al. 2016 [33]	CRB1, NEK7, MIR181	MYCN	SOX4, DEK	RBL2	45	SNP
Mol et al. 2014 [31]	KIF14, MDM4, LRNN2, ZNF281	MYCN, DDX1	DEK, E2F3, TNF, KIF13A, TDP2, CAP2, NUP153, SOX4, ID4	CDH11, CDH13, RBL2, MBTPS1, ZCCHC14, ZDHHC7	21	SNP
Sampieri et al. 2009 [4]	MCL1, SHC1, MUC1	MYCN, DDX1	IRF4, DEK, PIM1, E2F3, CCND3	CYLD, RBL2	18	CGH
Zielinski et al. 2005 [32]	SHC1, MDM4, GAC1	MYCN	TNF-alpha, HLA gene cluster	RBL2	17	CGH
Chen et al. 2001 [27]	LRNN2, REN, GAC1	MYCN	E2F3, ID4	CALB1, CBFB, CDH1, CDH11, CDH13, CDH15, CDH16, CDH3, CDH5, CDH8, E2F4, MAF, ZFHX3	50	CGH
Herzog et al. 2001 [28]		MYCN		RBL2	26	CGH