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. 2020 Aug 4;9(8):2514. doi: 10.3390/jcm9082514

Table A1.

Analysis of differences between malignant and benign nodules. Student’s t and Mann–Whitney U * analyses. Thresholds, sensitivity, specificity, and AUCs are based on the ROC curves for each keV energy level in AP.

Parameter keV (AP) Malignant
(n = 46)
Benign
(n = 19)
p-Value Thresholds Sensitivity (%) Specificity (%) AUC
Mean * Median SD * Range Mean * Median SD * Range
40 * 154.76 * 77.17–399.58 * 104.56 * 70.07–178.5 0.001 134.10 72 74 0.761
45 * 129.46 * 63.48–317.39 * 85.80 * 59.65–142.52 <0.001 106.08 74 74 0.783
50 * 109.70 * 52.36–251.17 * 68.42 * 51.26–113.57 <0.001 84.19 76 74 0.800
55 * 94.93 * 43.86–200.01 * 59.34 * 44.54–92.55 <0.001 93.99 54 100 0.827
60 * 80.87 * 35.33–151.58 * 47.61 * 35.25–75.57 <0.001 52.32 84 79 0.849
65 * 65.92 * 28.62–116.34 * 35.60 * 26.69–65.39 <0.001 53.99 70 95 0.852
70 * 59.16 * 25.78–95.00 * 32.67 * 21.19–57.62 <0.001 48.32 67 94 0.855
75 50.27 14.46 30.96 10.14 <0.001 43.38 67 94 0.851
80 45.83 12.87 28.03 10.30 <0.001 40.02 70 89 0.849
85 42.10 12.16 25.08 10.45 <0.001 38.51 67 95 0.854
90 38.13 11.47 22.04 10.58 <0.001 36.66 65 95 0.846
95 34.64 11.14 19.61 10.84 <0.001 32.32 65 89 0.824
100 32.23 11.00 17.66 11.10 <0.001 28.70 67 84 0.823
105 30.08 10.98 16.05 11.34 <0.001 27.83 60 89 0.811
110 28.06 11.04 14.54 11.59 <0.001 26.76 59 89 0.800
115 26.56 11.13 13.42 11.78 <0.001 23.31 63 84 0.791
120 25.14 11.25 12.37 11.97 <0.001 26.29 52 94 0.776
125 23.91 11.38 11.79 11.82 <0.001 26.25 50 95 0.768
130 22.89 11.52 10.69 12.30 <0.001 25.14 50 95 0.761
135 21.91 11.65 9.96 12.45 <0.001 23.39 52 95 0.757
140 21,3 11,98 9,45 12,47 <0.001 22.95 52 95 0.752

* non-normal distribution.