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. 2020 Jul 24;10(8):303. doi: 10.3390/metabo10080303

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© 2020 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Description of reviewed approaches to integrate omics data and the outcome of the modelling methods. Different omics data types can be generated in order to study different metabolism phenomena. Those omics data correspond to different layers of cell functioning. Collected omics data can be formalized in different modelling approaches as different layers of the hierarchical organization of biological systems. Conventional ways of integration are shown with arrows pointing to the equation part. The typical outcomes of the modelling approaches described in this review are highlighted.