Table 2.

List of investigational drugs currently being tested for COVID-19.

Drugs	Antiviral Activity	Number of Clinical Trials	Reference
Remdesivir	RdRp inhibitor	10	[171]
Tradipitant	Neurokinin-1 (NK1) antagonist	1	[173]
ASC09 or TMC 310911	Human immunodeficiency virus-1 (HIV-1) protease inhibitor	1	[174]
FT516	i. Genetically modified natural killer (NK) cells ii. Enhances cytotoxic response against SARS-CoV-2	1	[175]
CD24Fc	Immune check point and prevents hyperinflammation	1	[176,177]
XPro1595	Tumor necrosis factor (TNF) inhibitor	1	-
LY3127804	Angiopoietin-2 antibody	1	[178]
Leronlimab	C-C chemokine receptor type 5 (CCR5) antibody	2	[179]